Ellen Pompeo

 Well, what would Grey’s Anatomy be without Ellen Pompeo’s character Dr. Meredith Grey? In a recent interview with Entertainment Weekly, Pompeo, who’s contract is only through season 16, hinted that 2020 may be her last year on the medical drama. “I’m feeling like we’re coming to the end of the stories that we’ve told and that we can tell,” she said. “I’m really excited to do some new things, it’s about time that I mix it up and I’m really excited about my producing career, and I’m definitely looking for a change.” In 2017, show creator Shonda Rhimes told E! News, “Ellen and I have a pact that I’m going to do the show as long as she’s going to do the show. So the show will exist as long as both of us want to do it. If she wants to stop, we’re stopping. So I don’t know if we’ll see 600, but I want to keep it feeling fresh.”